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Corinna Singleman

Corinna Singleman

Managing Editor at Genetic Engineering & Biotechnology News

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Location
United States
Languages
  • English
Covering topics
  • Biotechnology
  • Health & Medicine

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Recent Articles

genengnews.com

Improving Astrocyte Function Shows Promise for Alzheimer’s Mouse Model

The study evaluates the long-term cognitive abilities in the mice with overexpression of Sox9 or elimination of the gene.
genengnews.com

NIH Funding Cuts’ Impact on Drug Discovery and Development

Proposed NIH funding cuts are a pressing concern when one considers the broader impacts of reduced research funding.
genengnews.com

Malaria-Transmitting Mosquito’s Genetic Diversity and Evolution Rev...

Little is known about the genetics of Anopheles funestus, one of the most prolific malaria-transmitting mosquitos in sub-Saharan Africa.
genengnews.com

Single-Cell Proteomics Reveal Hidden Layers of Gene Expression

Single-cell proteomics with RNA sequencing uncover hidden gene expression dynamics in stem cell differentiation.
genengnews.com

Alzheimer’s Therapy Delivery Boosted with Engineered Antibody

The newly designed antibody transport vesicle holds promise as a potential solution to the challenges of current AD therapies.
genengnews.com

Protein Core Stability Rules Open Door for Faster Protein Design

Large-scale redesigns, including changes to core domains, may retain stability—challenging assumptions that such regions are off-limits.
genengnews.com

Protein Dynamics Predicted Rapidly with Generative AI Model, BioEmu

A newly developed generative AI model is helping researchers explore protein dynamics with increased speed.
genengnews.com

Genetic “Dimmer Switch” Offers Precise Gene Expression Control

The duration of expression of the gene Cdx2 is tightly regulated by a newly identified DNA sequence element called an “attenuator.”
genengnews.com

AI-Designed Proteins Created De Novo with New AlphaDesign

By designing proteins de novo scientists can more efficiently create novel therapeutics tailored for specific biological functions.
genengnews.com

Viral Ribosome Profiling Could Speed Vaccine Development

Massively Parallel Ribosome Profiling (MPRP) enables rapid identification of viral proteins without the need to grow live viruses.
genengnews.com

More Mutations in Childhood Cancer Might Mean More Therapy Options

The increased genetic complexity and similarity to adult cancers’ genetic diversity could also present new therapeutic opportunities.
genengnews.com

SARS-CoV-2 Likely Spread Through Wildlife Trade, Not Bat Migration

The virus likely reached humans not via bat migration but through the wildlife trade—contradicting hypotheses that it may have lab origins.
genengnews.com

Sugar Swap Leads to Sweet Spot in Creating "Super Stem Cells"

A small shift in nutrient supply has led to the development of a new method to rejuvenate stem cells.
genengnews.com

GLP-1 Drugs Effectiveness Reduced by Neurons That Control Overeating

Researchers identified how a brain circuit involving dopamine and GLP-1 receptor impact palatability and hedonic eating.
genengnews.com

Macrophages Fight COVID-19-Induced Lung Damage with Peroxisomes

Research identifies how viral respiratory infection damages macrophages and suggests treatment with a pre-existing FDA approved drug.
genengnews.com

Genetic Engineering at Asilomar, Stand Up for Science, and Francis ...

GEN editors discuss both the news and history of DNA and genetic engineering in this episode of the Touching Base Podcast.
genengnews.com

Scientists in NYC Rally to Defend and Stand Up for Science

The crowd was loud and energized, speaking in one unified voice with a major message: “Science, not silence.”
genengnews.com

Tardigrade Protein Protects Healthy Cells from Radiation Damage

This approach could transform radiation therapy by allowing higher doses to be used more safely, ultimately improving outcomes for cancer patients.
genengnews.com

Fragile X Phenotypes Reversed in Mice by Targeting NMDA Receptors

MIT researchers suggests a potential molecular strategy for treating fragile X syndrome by enhancing NMDA subunit function.
genengnews.com

AI-Driven Protein Design Produces Enzyme that Mimics Natural Hydrol...

New research uses AI to engineer enzymes with intricate active sites, expanding the possibilities for synthetic biocatalysts.
genengnews.com

Obesity-Linked Hormone Adrenomedullin Disrupts Insulin Signaling

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes.