Data from US pharmacies indicates the volume of outpatient antibiotic prescriptions, after falling sharply in 2020 and 2021, rose to 2019 levels by the end of 2022.
Researchers found that a daptomycin-resistance mutation in vancomycin-resistant Enterococcus faecium is linked to use of rifaximin, an antibiotic prescribed for patients with liver cirrhosis.
The Italian government will contribute $21 million over 3 years to support CARB-X’s efforts to advance early-stage development of innovative new products for drug-resistant pathogens.
After surging during the pandemic, rates of carbapenem-resistant gram-negative bacteria in critically ill patients have declined but remain higher than pre-pandemic rates.
The project will begin with research into an at-home, inhalable treatment containing probiotics and prebiotics that can combat lung infections caused by Pseudomonas aeruginosa.