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Caroline Helwick

Caroline Helwick

Freelance Medical Writer at The ASCO Post

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Location
United States
Languages
  • English
Covering topics
  • Health & Medicine

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Recent Articles

ascopost.com

Exploratory FLAURA2 Analysis Confirms Overall Survival Benefit for Osimertinib in NSCLC Subgroups

An exploratory overall survival analysis of the phase III FLAURA2 trial confirmed the overall survival benefit of adding osimertinib to chemotherapy in patients with non–small cell lung cancer (NSCLC)...
ascopost.com

HER2-Positive Early Breast Cancer: Trastuzumab Deruxtecan Moves Int...

Two pivotal studies of fam-trastuzumab deruxtecan-nxki (T-DXd) in early HER2-positive breast cancer suggest this antibody-drug conjugate (targeting the HER2 protein) may be moving into the curative se...
ascopost.com

Contemporary Management of Chronic Myeloid Leukemia, According to H...

Chronic myeloid leukemia (CML) is one of the success stories among the hematologic malignancies. Now, with decades of data informing its management, it is time to change some of the practices to which...
ascopost.com

In Extensive-Stage Small Cell Lung Cancer Novel Maintenance Regimen...

The phase Ib DeLLphi-303 trial has reported overall survival data for a novel maintenance regimen in extensive-stage small cell lung cancer following first-line chemoimmunotherapy. Patients treated wi...
ascopost.com

In Extensive-Stage Small Cell Lung Cancer Novel Maintenance Regimen...

The phase Ib DeLLphi-303 trial has reported overall survival data for a novel maintenance regimen in extensive-stage small cell lung cancer following first-line chemoimmunotherapy. These findings were...
ascopost.com

Smoldering Multiple Myeloma: How the Guidance Is Changing

Clinical trials have sought to determine the benefit of treating the precursors of multiple myeloma, but as the phenotypes and genomics of this entity are becoming better delineated, the wisdom of ear...
ascopost.com

Experimental Approach to Graft-vs-Host Disease Prophylaxis Offers A...

Prevention of graft-vs-host disease was far superior with a cyclophosphamide/cyclosporin-based regimen than with standard prophylaxis in patients receiving a matched-sibling donor stem cell transplant...
ascopost.com

Smoldering Multiple Myeloma: How the Guidance Is Changing

Smoldering Multiple Myeloma: How the Guidance Is Changing
ascopost.com

Polatuzumab Vedotin–Based Regimen Improves Overall Survival in Refr...

Combining the CD79b-directed antibody-drug conjugate polatuzumab vedotin-piiq with rituximab, gemcitabine, and oxaliplatin (R-GemOx) significantly improved survival outcomes in patients with transplan...
ascopost.com

Polatuzumab Vedotin–Based Regimen Improves Overall Survival in Refr...

Combining the CD79b-directed antibody-drug conjugate polatuzumab vedotin-piiq with rituximab, gemcitabine, and oxaliplatin (R-GemOx) significantly improved survival outcomes in patients with transplan...
ascopost.com

Polatuzumab Vedotin–Based Regimen Improves Overall Survival in Refr...

Combining the CD79b-directed antibody-drug conjugate polatuzumab vedotin-piiq with rituximab, gemcitabine, and oxaliplatin (R-GemOx) significantly improved survival outcomes in patients with transplan...
ascopost.com

A Potential New Standard of Care in Gastric or Gastroesophageal Jun...

In patients with resectable gastric or gastroesophageal junction (GEJ) adenocarcinoma, perioperative treatment with the checkpoint inhibitor durvalumab in combination with standard chemotherapy signif...
ascopost.com

Use of Adjuvant Aspirin Reduces the Risk of Recurrence in PI3K -Mut...

Use of Adjuvant Aspirin Reduces the Risk of Recurrence in PI3K -Mutated Colorectal Cancer
ascopost.com

Phase III Trial Results Suggest a New Standard of Care in Metastati...

In the phase III DESTINY-Breast09 trial, first-line treatment with the antibody-drug conjugate fam-trastuzumab deruxtecan-nxki (T-DXd) plus the monoclonal antibody pertuzumab significantly delayed dis...
ascopost.com

Adjuvant Use of Atezolizumab Plus Chemotherapy in DNA Mismatch Repa...

For the adjuvant treatment of stage III colon cancer with DNA mismatch repair–deficient (dMMR) tumors, the addition of the checkpoint inhibitor atezolizumab to standard chemotherapy significantly impr...
ascopost.com

Use of Adjuvant Aspirin Reduces the Risk of Recurrence in PI3K -Mut...

Use of Adjuvant Aspirin Reduces the Risk of Recurrence in PI3K -Mutated Colorectal Cancer
ascopost.com

Use of Adjuvant Aspirin Reduces the Risk of Recurrence in PI3K-Muta...

Use of Adjuvant Aspirin Reduces the Risk of Recurrence in PI3K-Mutated Colorectal Cancer
ascopost.com

Experimental Approach to GVHD Prophylaxis Offers Alternative to Sta...

Prevention of graft-vs-host disease (GVHD) was superior with a cyclophosphamide/cyclosporin-based regimen compared with standard prophylaxis in patients receiving a matched-sibling donor stem cell tra...
ascopost.com

Conundrums in Treating HER2-Positive Early Breast Cancer

Today’s oncologists are blessed with an abundance of therapies for HER2-positive early breast cancer, but this comes with the challenge of selecting among them. At the 2025 Miami Breast Cancer Confere...
ascopost.com

Recent Advances in Treating Diffuse Large B-Cell Lymphoma

The disease we now call diffuse large B-cell lymphoma (DLBCL) has gone by the names of reticulum cell sarcoma, diffuse histiocytic lymphoma, and diffuse large cell lymphoma and included both lymphomas...
ascopost.com

Recent Advances in Treating Diffuse Large B-Cell Lymphoma

The disease we now call diffuse large B-cell lymphoma (DLBCL) has gone by the names of reticulum cell sarcoma, diffuse histiocytic lymphoma, and diffuse large cell lymphoma and included both lymphomas...