Savannah Demko

In a video interview, Nancy Lin, MD, of Dana-Farber Cancer Institute, discussed “interesting updates” from the NATALEE trial presented at ESMO Congress.The study showed the efficacy of adjuvant ribociclib (Kisqali, Novartis) plus nonsteroidal aromatase inhibitor in patients with HR-positive, HER2-negative early breast cancer.

Trastuzumab deruxtecan showed substantial and durable overall and intracranial clinical activity in patients with HER2-positive metastatic breast cancer, according to results from the DESTINYBreast-12 trial presented at ESMO Congress. Importantly, trastuzumab deruxtecan, also known as T-DXd, (Enhertu; AstraZeneca, Daiichi Sankyo) exhibited these benefits in a large cohort with stable and active

Nancy Lin, MD, from the department of medical oncology at Dana-Farber Cancer Institute, discussed exciting OS data from the KEYNOTE-522 study presented at ESMO Congress. The study showed that neoadjuvant pembrolizumab (Keytruda, Merck) plus chemotherapy followed by adjuvant pembrolizumab resulted in a statistically significant and clinically meaningful improvement in OS compared with

Breastfeeding appeared safe in women with hormone receptor–positive early breast cancer who temporarily interrupted treatment to attempt pregnancy, according to results from the POSITIVE trial presented at ESMO Congress. “I think that the main takeaway from this study is that women are motivated to breastfeed after a breast cancer diagnosis and interrupting treatment to have a child,

In a video interview with Healio, Chandrajit Raut, MD, MS, discussed highlights from “one of the best” Connective Tissue Oncology Society meetings he has attended. Raut, chief of surgical oncology at Brigham and Women’s Hospital, surgical director of the Dana-Farber Brigham Cancer Center sarcoma and bone oncology programs, and professor of surgery at Harvard Medical School,

Chandrajit Raut, MD, MS, talked about a video session at the Connective Tissue Oncology Society Annual Meeting on approaching oncologic surgery for sarcoma specialists.The session featured videos submitted by experts on decision-making, artificial intelligence technology, computer-generated imaging, 3D imaging for operation planning, center-specific techniques and more, according to Raut,

Candace Haddox, MD, explored advances in genetic sequencing for sarcomas, which was a major theme of the Connective Tissue Oncology Society Annual Meeting, in this video interview with Healio.“We’re making progress on two key fronts: the first is gaining a better understanding of heterogeneity not only across sarcoma subtypes, but even within subtypes and within single patients;

In this video, Candace Haddox, MD, discussed a few presentations from the Connective Tissue Oncology Society Annual Meeting that focused on how better understanding of sarcoma biology could lead to clinical advancement.“We are seeing progress in understanding sarcoma biology and, importantly, we’re incorporating this knowledge into rational clinical trial and drug development that

Sandra D’Angelo, MD, discussed a clinical trial on trabectedin in combination with low-dose irinotecan in Ewing sarcoma presented at the Connective Tissue Oncology Society Annual Meeting.“The combination together was found to be quite efficacious,” D’Angelo, research director of the sarcoma medical oncology service at Memorial Sloan Kettering Cancer Center, said in

In this video, Sandra D’Angelo, MD, discussed a phase 1b study on the efficacy and safety of botensilimab plus balstilimab in patients with refractory metastatic sarcoma presented at the Connective Tissue Oncology Society Annual Meeting.“There was some efficacy described in leiomyosarcomas as well as visceral sarcomas, which is interesting considering some other efforts with