Matthew Shinkle

CHICAGO — Adding niraparib to abiraterone acetate and prednisone may help slow cancer growth for patients with metastatic castration-sensitive prostate cancer with homologous recombination repair gene alterations.Findings of the AMPLITUDE trial, presented at ASCO Annual Meeting, build on previous data from the MAGNITUDE trial, which led to the approval of niraparib with abiraterone acetate

Rates of past-month binge drinking were higher among women than men aged 18 to 25 years from 2021 to 2023, reversing trends between the two groups from 2017 to 2019, according to study results published in JAMA.“We published a study in JAMA Health Forum about a year ago, where we found a sharp increase in alcohol-related hospitalizations among middle-aged and young adult women during the

Despite recent increases in postdischarge pharmacotherapy for patients admitted with alcohol-associated liver disease, psychiatric referrals or outpatient follow-ups remain low, according to research published in JAMA Network Open.Men and patients with cirrhosis had lower rates of pharmacologic cessation prescriptions and psychiatric referrals, results showed, highlighting a need for treatment

Patients with certain subtypes of breast cancer may be at higher risk for death by waiting more than 42 days after their diagnosis to undergo surgery, according to study results published in Breast Cancer Research.Patients with HR+ or HER2-negative breast cancer appeared to be affected the most, findings showed. Mortality risk increased by 21% after 60 days, by 79% after 90 days and 183% after

Incidence and mortality rates for uterine cancer are projected to rise substantially over the next 3 decades, according to research published in Cancer Epidemiology, Biomarkers & Prevention.Racial disparities also are expected to become more pronounced, with incidence-based mortality predicted to be nearly three times higher among Black women than white women by 2050.

The number of opioid-related deaths with concurrent gastrointestinal complications in the United States more than tripled from 2010 to 2020, with men and individuals living in the Appalachian region disproportionately affected.The data, published in Cureus, highlight the importance of not just looking at overdose deaths and incidence, but also factoring in other long-term medical complications as

An algorithm-enabled service that analyzes raw imaging data aims to help oncologists make the most informed decisions about treatment for patients with late-stage cancer.AIQ Solutions, based in Madison, Wisconsin, uses advanced technology to assess serial radiographic images and deliver a comprehensive report to oncologists, who can then tailor treatment regimens and optimize outcomes for

The FDA has approved the Idylla CDx MSI test — a fully automated, “sample-to-result” companion diagnostic — for patients with colorectal cancer, according to a press release.The test, developed by Biocartis in partnership with Bristol Myers Squibb, helps identify patients with microsatellite instability-high (MSI-H) CRC who may benefit from treatment with nivolumab

The FDA has granted orphan drug designation to ligufalimab, a CD47 monoclonal antibody, for treatment of acute myeloid leukemia.According to a press release, ligufalimab (AK117, Akeso) is being evaluated for both hematologic malignancies and solid tumors, with two phase 3 studies underway. Both studies are assessing its efficacy in combination with ivonescimab (SMT112, Summit Therapeutics) as a

An online risk assessment service seeks to help women better understand their risk for breast cancer and take action to prevent late-stage diagnoses.Gabbi offers a clinically validated digital risk assessment, followed by a virtual visit with a certified nurse practitioner who helps women understand their risk, orders necessary tests or imaging, and develops a care plan to manage and reduce their