Patients who underwent medial opening wedge high tibial osteotomy had less structural joint damage and improved outcomes at 2 years compared to those who received nonsurgical management only.
EULAR now recommends moving directly to biologic or targeted synthetic disease-modifying antirheumatic drugs if the initial methotrexate therapy fails.
Different vasoactive vasodilating drugs were associated with protective effects depending on patients' vasculopathy, but exposure to these drugs did not affect overall survival.