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Isabella Hornick

Isabella Hornick

Author at healio.com at Healio

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22
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United States
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  • English
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    Recent Articles

    healio.com

    Nebulized clofazimine trial in nontuberculous mycobacterial lung disease discontinued

    After assessing data from the first 46 adults with refractory nontuberculous mycobacterial lung disease who completed the ICoN-1 trial double-blind treatment phase, the trial is being discontinued, according to a press release. This multinational, randomized, double-blind, placebo-controlled phase 3 registrational study was analyzing the efficacy and safety of nebulized clofazimine inhalation
    healio.com

    Odds for mortality in COPD exacerbation hospitalization lower with ...

    CHICAGO — Patients hospitalized for acute COPD exacerbation had reduced odds for in-hospital mortality if they had a prior history of bariatric surgery, according to data presented at the CHEST Annual Meeting.“Our findings are consistent with superior outcomes in patients admitted for acute exacerbation of COPD who had received prior bariatric surgery compared to those who did
    healio.com

    KALOS, LOGOS: Triple therapy inhaler improves lung function in asthma

    CHICAGO — A single-inhaler triple therapy improved lung function in adults and adolescents with inadequately controlled asthma and was superior to the standard of care inhaler, according to data from two phase 3 trials.“This reinforces the positive impact of triple therapy on patients with asthma uncontrolled on inhaled corticosteroids/long-acting beta agonists and provides us with
    healio.com

    Ensifentrine improves dyspnea, symptoms, quality of life in COPD wi...

    CHICAGO — Dyspnea and quality of life improved with receipt of ensifentrine in a subgroup of adults with moderate to severe COPD without an exacerbation during the trial period, according to data presented at the CHEST Annual Meeting.“As clinicians, we see many patients with COPD who continue to have symptoms despite reducing exacerbation with standard of care therapies, [and] our
    healio.com

    Active cigarette smoking linked to elevated pneumonia rates in COPD

    CHICAGO — A significant link was found between active cigarette smoking and an elevated rate of pneumonia in COPD, whereas this was not true for active e-cigarette or cigar smoking, according to data presented at the CHEST Annual Meeting.“We demonstrated that adults with COPD have higher rates of acquiring pneumonia over a 12-month timeframe if they are actively smoking
    healio.com

    GLP-1 receptor agonists linked to lower mortality, respiratory fail...

    CHICAGO — Adults with pulmonary arterial hypertension using vs. not using GLP-1 receptor agonists had significantly lower relative risks for mortality and respiratory failure, according to a presentation at the CHEST Annual Meeting.In a retrospective study, Saud Alawad, MBBS, third-year internal medicine resident at West Virginia University, and colleagues analyzed adults with a group 1 PAH
    healio.com

    Dupilumab benefits patients with COPD regardless of cardiovascular,...

    Among adults with COPD and type 2 inflammation, having a history of cardiovascular or metabolic disease did not change benefits seen with dupilumab, according to a poster presented at the European Respiratory Society International Congress.“Dupilumab is already approved for eligible patients with COPD, and these findings emphasize that the presence of cardiovascular and metabolic
    healio.com

    FDA approves Eydenzelt as biosimilar referencing Eylea

     The FDA approved Eydenzelt, a biosimilar referencing Eylea, for the treatment of four retinal diseases, according to a press release from Celltrion.
    healio.com

    Immune cells increase with exercise-based rehabilitation in post-CO...

    Individuals with post-COVID syndrome had higher immune cell counts after receiving exercise-based rehabilitation vs. usual care for 8 weeks, according to data presented at the European Respiratory Society International Congress.“Clinicians should consider exercise-based interventions for people with long COVID to improve exercise capacity and immune function,” Enya Daynes, PhD, MCSP,
    healio.com

    Paternal smoking during puberty linked to epigenetic age accelerati...

    Paternal smoking during puberty was linked to epigenetic age acceleration in female offspring determined via three epigenetic clocks, according to data presented at the European Respiratory Society International Congress.Epigenetic age is “a cellular biomarker derived from DNA methylation patterns that reflects biological aging,” according to the study poster.
    healio.com

    Dietary diversity during pregnancy impacts risk for infant atopic d...

    Consuming a diverse diet during pregnancy may reduce the risk for atopic dermatitis in offspring by changing the infant gut microbiome, according to results published in Pediatric Allergy and Immunology. “Our research strengthens the body of evidence on a link between a diverse maternal diet during pregnancy and reduced onset of AD (eczema) in the offspring during the crucial first 3years of