Cam Inman

The 49ers (6-3) are scrambling again on defense as they prepare to host the Los Angeles Rams (6-2) on Sunday.

Offense shines in road win, but Williams’ injury more bad luck heading into showdown vs. Rams at Levi’s Stadium

The 49ers’ meek offense blamed itself rather than a young, patchwork defense for Sunday’s 26-15 loss at Houston.

“We like being overlooked,” Alfred Collins added. “Count us out if you want. Just turn on the tape and you’ll see what’s up.”

The 49ers had only 10 defenders on the field when Fred Warner’s ankle injury occurred, and so much more went wrong en route to a 31-19 loss at Tampa Bay.

The 49ers ruled out Brock Purdy for the fourth time this season and plan to have Mac Jones start Sunday’s visit to Tampa Bay.

The 49ers (4-1) are alone atop the NFC West after their overtime thriller against the host Rams (3-2).

The 49ers (3-1) must find a way to pressure the Rams’ Matthew Stafford without Nick Bosa and also contain NFL-leading wide receiver Puka Nacua.

The 49ers defense and coordinator Robert Saleh — fresh off a public spat with Jacksonville coach Liam Coen — face a tough task Thursday night visiting the Los Angeles Rams.

The 49ers will re-evaluate Brock Purdy’s sore toe from Sunday’s loss to the Jaguars and with a Thursday game fast approaching at the Los Angeles Rams.